Research into germline DNA alterations that predispose to colorectal cancer

The Gastrointestinal and Pancreatic Oncology Team of STEPUPIORS PI Dr Sergi Castellví-Bel from the Fundació de Recerca Clínic Barcelona-Institut d’Investigacions Biomèdiques August Pi i Sunyer (FRCB-IDIBAPS) and Hospital Clínic de Barcelona aims at deciphering alterations in germline DNA that predispose to colorectal cancer.

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March 13-14, 2023, "How to build a biobank" Training at Medical University Graz, Austria

STEPUPIORS participants attended a productive biobanking training with interesting networking at Medizinische Universität Graz in the beautiful city of Graz, Austria, in the period March 13-14, 2023.
Along with great efforts and a lot of precious knowledge that was previously poured into the future IORS biobanking staff by partner institutions, STEPUPIORS biobanking will officially start on April 01, 2023.

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Lecture at "Next Generation Scientists" meeting in Belgrade, Serbia

STEPUPIORS project participants Dr Marija Đorđić Crnogorac and Katarina Živić participated at the “Next Generation Scientists” meeting in Belgrade, Serbia on March 09, 2023. Dr Đorđić Crnogorac gave a lecture on genetic testing of hereditary cancers including Lynch syndrome using NGS methodology at the Institute for Oncology and Radiology of Serbia. The process and criteria for Lynch syndrome testing were presented as well as results from the period 2018-2023.

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Outreach event in collaboration with Researcher's Night project ScienceSCool

Members of the STEPUPIORS team, Dr Ana Đurić and Aleksandra Stanojević, had the honor and pleasure to discuss with students of the Gymnasium Svetozar Marković in Subotica, through an interactive presentation, how healthy lifestyle habits play a crucial role in the prevention of colorectal cancer. The significance of stronger involvement of young students in scientific research was also highlighted in an effort to engage young generations in the advancement of science in Serbia.
The event was organized by European Researcher’s Night project Science on the move – from lab to streets & school (ScienceSCool – 101061631).

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Expert insights about novel biomarkers for colorectal cancer from the TRANSCOLONCAN COST Action by Dr Sergi Castellví-Bel

STEPUPIORS PI from FRCB-IDIBAPS Dr Sergi Castellvi-Bel shared expert insights about the significant progress made in identifying novel biomarkers for colorectal cancer within and beyond the inspiring and productive TRANSCOLONCAN COST Action he chaired.

Dr Castellvi-Bel outlined that TRANSCOLONCAN aimed at improving  colorectal cancer screening, early detection, and monitoring by using liquid-biopsy approaches and better tumour profiling. The network also explored the use of CRISPR-Cas9 and immunotherapy to develop new treatments for the disease. He highlighted that over the past four years, several objectives were accomplished, including both scientific achievements and involvement of COST Inclusiveness Target Countries (ITC), young, and female researchers. The publication of the results of the genome-wide association studies from the EU and USA consortia was a significant milestone. Additionally, Milena Cavic, a young researcher from Serbia, received a Horizon Europe Twinning project STEPUPIORS, which was also a noteworthy achievement.
For more information, please read the full interview:

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STEPUPIORS PI Dr Sergi Castellví-Bel from FRCB-IDIBAPS in COST News

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Feb 13-15, 2023, Visit of IORS delegation to the Netherlands Cancer Institute Antoni van Leeuwenhoekziekenhuis (NKI AVL)

STEPUPIORS clinicians and researchers Dr Suzana Stojanović-Rundić, Dr Ana Đurić, Dr Marko Radulović, Dr Radmila Janković, Dr Miljana Tanić, Dr Marija Đorđic Crnogorac and Dr Milena Čavić had the privilege to visit the Netherlands Cancer Institute Antoni van Leeuwenhoek Ziekenhuis (NKI-AVL) during the period of Feb 13-15, 2023 . During the visit, which was brilliantly hosted by Dr Remond Fijneman, IORS staff members explored first hand strategies for efficient integration of clinical and translational biomedical research in a top-ranked European institution.
IORS project management staff got acquainted with the project management structure and local practice, leading to a transfer of knowledge into the future IORS Research Management Office. IORS biobanking members also explored the biobanking practice at NKI AVL, which laid a solid foundation for the future setting up of the IORS rectal cancer biobank, combined with expert advice from other project partner institutions. IORS staff also visited the Bioimaging and Genomics core facilities, as well as the Radiotherapy Clinic. The visit was very successful with the participation of many NKI AVL staff members: Dr Baukelien Van Triest, Dr Marjolijn Mertz, Dr Beatriz Carvalho, Dr Roderick Beijersbergen, Carmen Rubio Alarcón, Soufyan Lakbir, Dr Paula Hoekstra, Dr Omied M. Horati, Dr Sacide Ekiz, Dr Meike de Wit, Dr Gerrit Meijer, Dr Henri Van Luenen, Dr Susanne Rebers, Dr Annegien Broeks, Dr Hylke Galama, Dr Lana Ster-Meiqari, Dr Wouter Kievit, Dr Mariska Bierkens Margriet Lemmens and Dr Daan van den Broek.

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STEPUPIORS in Hospital Clínic de Barcelona News

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January 27, 2023, Regional Twinning project meeting "Twinning projects: Experiences and obstacles 2"

STEPUPIORS members Dr Ana Đurić and Dr Milena Čavić participated at an inspiring regional Twinning project meeting “Twinning projects: Experiences and obstacles 2”, organized by Dr Goran Ristić and the ELICSIR Project from the University of Niš, Faculty of Electronic Engineering, on January 27, 2023. During the meeting, STEPUPIORS Project Coordinator Dr Milena Čavić presented the project scientific aims, mission, vision, communication, and management strategy and outlined current implementation challenges and obstacles. During round table discussions, Dr Ana Đurić discussed with other Twinning project participants from Serbia and Romania on possible strategies for further collaboration and overcoming main jointly identified implementation challenges – bureaucratic issues, lack of coordinated governmental project management support and lack of sufficient number of qualified national project managers.

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