STEPUPIORS free online workshop: OMICS DATA GENERATION AND INTEGRATION WITH CLINICAL INFORMATION
June 01–02, 2023
STEPUPIORS team invites you to join the exciting online training within WP2 entitled “Omics data generation and integration with clinical information”. The workshop will address the main principles of proteomics, transcriptomics, and genomics along with computational tools for integrating omics datasets and linking them to clinical data. Statistical and bioinformatics tools available for the analysis of omics and clinical data will also be presented during this two-day workshop.
Login information:
Thursday June 1st
(Athens time, GMT+3)
Topic: STEPUPIORS workshop – Omics data generation and integration with clinical information – Day 1
Time: Jun 1, 2023 09:00 AM
Join Zoom Meeting
https://us06web.zoom.us/j/
Meeting ID: 856 8278 8875
Passcode: 870977
Friday June 2nd
(Athens time, GMT+3)
Topic: STEPUPIORS workshop – Omics data generation and integration with clinical information– Day 2
Time: Jun 2, 2023 09:00 AM
Join Zoom Meeting
https://us06web.zoom.us/j/
Meeting ID: 876 2608 4546
Passcode: 172706
Lectures at “Biochemistry in service of health – modern approaches in biomedical research” student course
During the period May 14-20, 2023, STEPUPIORS team members Aleksandra Stanojević, Ana Đurić and Milena Čavić participated as lecturers at the course “Biochemistry in service of health – modern approaches in biomedical research”, organized by the Biochemical Society of Serbia in Belgrade and Novi Sad, Serbia. Dr Čavić gave a lecture “Molecular genetics methods in modern diagnostics and scientific research” during which she promoted the STEPUPIORS project and invited interested students from 4 Universities in Serbia (University of Belgrade, University of Novi Sad, University of Niš, University of Kragujevac) to join the efforts of profiling new predictive biomarkers for rectal cancer in their future studies. Ms Stanojević discussed her PhD work on rectal cancer within the project with students and answered questions regarding the specificities of working in a health research center. Dr Đurić discussed with students about using cell cultures for metabolomics approaches and functional validation of identified biomarkers for rectal cancer.
The students were very interested in all aspects of the presented work, and expressed wishes for a follow-up visit to the Institute for Oncology and Radiology of Serbia and further studies on the topic within their Masters and PhD thesis.
First scientific publication within WP2
Check out the first exciting STEPUPIORS Project scientific results by Aleksandra Stanojević, Martina Samiotaki, Vasiliki Lygirou, Mladen Marinkovic, Vladimir Nikolic, Suzana Stojanovic-Rundic, Radmila Jankovic, Antonia Vlahou, George Panayotou, Remond Fijneman, Sergi Castellvi-Bel, Ieronymos Zoidakis and Milena Cavic!
Stanojevic A, Samiotaki M, Lygirou V, Marinkovic M, Nikolic V, Stojanovic-Rundic S, Jankovic R, Vlahou A, Panayotou G, Fijneman R.J.A, Castellvi-Bel S, Zoidakis J , Cavic M. Data independent acquisition mass spectrometry (DIA-MS) analysis of FFPE rectal cancer samples offers in depth proteomics characterization of response to neoadjuvant chemoradiotherapy. medRxiv 2023.05.12.23289671; doi: https://doi.org/10.1101/2023.05.12.23289671
STEPUPIORS Outreach event in Elementary School „Jovan Miodragović“ in Belgrade
This May, the STEPUPIORS team visited the fifth-grade students of the Elementary School “Jovan Miodragović” in Belgrade. Dr Milena Čavić, Dr Ana Đurić and Aleksandra Stanojević, as part of an educational workshop called “Healthy intestines – healthy us”, talked to the children about a healthy lifestyle. They tried to emphasize to pupils that the active implementation of a healthy lifestyle could improve the health of the entire nation and reduce the incidence of malignant diseases, with emphasis on malignancies of the digestive system. Information about healthy eating, the importance of physical activity and the harmfulness of bad habits such as smoking and excessive use of electronic devices was conveyed to children in a way adapted to their age through play, recognizing healthy foods, solving tests and making models of DNA molecules. The main aim of this workshop was to educate children about the fact that they need to take care of their own health in the future and that the effect of possibly present unfavorable hereditary factors can be significantly reduced by a healthy lifestyle.
The children showed good theoretical knowledge which, for various reasons, they still do not apply in their everyday life. Their desire is to acquire new knowledge through creative work with adults. Our obligation is to enable them to do so, which will first of all support their proper psychophysical development.
Participation at the 1st Open Balkan Digestive Oncology Expert Meeting
On May 12-13, 2023, STEPUPIORS team members Dr Radmila Janković, Dr Mladen Marinković and Dr Milena Čavić participated at the 1st Open Balkan Digestive Oncology Expert Meeting organized by the Association of Digestive Oncology of Serbia – ADOS, STEPUPIORS’ stakeholder. Dr Marinković participated as a panelist in a session “Rectal Cancer: More TNT, less surgery?” and highlighted the importance of project results from liquid biopsy expected in 2023/24. Dr Janković participated as a panelist in a session “Precision therapy in digestive oncology” and conveyed project aims to profile the response to neoadjuvant chemoradiotherapy in rectal cancer. Dr Čavić discussed on project aims and results with various target audience types: Research communities, Industry, Business partners, Innovators, Investors, EU Institutions, National authorities (representatives of the Ministry of Health), Regional authorities (Croatia, Slovenia, Montenegro), Local authorities (city council representatives) and Digestive Cancers Europe CEO Dr Zorana Maravić about the possibility to organize a joint event involving patients and patient representatives in Serbia.
The meeting was focused on digestive oncology and was very successful, connecting researchers and end users, enabling future joint initiatives.
The STEPUPIORS participated in the 13th Congress of the Serbian Society of Toxicology with international participation and the 1st TOXSEE Regional Conference
The STEPUPIORS team participated in the 13th Congress of the Serbian Society of Toxicology with international participation and the 1st TOXSEE Regional Conference entitled “Present and Future of toxicology: challenges and opportunities“, which were held from May 10 to 12, 2023 in Belgrade. Dr. Ana Đurić presented the joint work of members of the STEPUPIORS Twinning project entitled “Is there a relation between hematological toxicity and response to neoadjuvant chemoradiotherapy in patients with locally advanced rectal cancer?” whose objective was to evaluate the association between hematologic toxicity and tumor response to therapy. The research included 75 patients, who were treated at the Institute of Oncology and Radiology of Serbia in the period from June 2020 to January 2022. By further targeted monitoring of defined hematological parameters, the study will provide answers that contribute to the progress of a personalized approach to the treatment of patients with this malignancy disease.
During the three days of the congress, participants had the opportunity to listen to lectures by colleagues from Serbia and abroad, which covered a wide range of important topics in the field of contemporary toxicology. It was an honor and pleasure for us to share our results with our colleagues, as well as to participate in a meeting of exceptional educational and scientific importance for our community.
ELISA training at IORS
Dr Ana Vuletić and Dr Katarina Mirjačić Martinović organized a basic two-day course related to ELISA method for IORS project participants and other interested IORS colleagues.
During the first day, theoretical principles of ELISA method were presented, while the second day was dedicated to a practical step-by-step approach how sandwich ELISA works. As a practical exercise the level of IL-10 in the sera was analyzed.
Thanks to the excellent organization of the course, all attendees were thoroughly trained to construct a standard curve and determine the concentration of IL-10 in serum samples. The participants of the course, Aleksandra Stanojević, Kristina Živić, Katarina Živić, Miodrag Vuković, Maja Petrović, and Dušica Petrović are now ready to successfully perform the ELISA method independently.