New project publication
Aleksandra Stanojevic published a third manuscript with her PhD results on the analysis of public bulk RNA-seq data to identify predictive features of response to nCRT in rectal cancer. These findings provide insight into mechanisms underlying therapy response, as a first meta-analysis using high-throughput sequencing data.
Stanojevic, A., Stroggilos, R., Marinkovic, M., Djuric, A., Stojanovic‐Rundic, S., Jankovic, R., Castellvi‐Bel, S., Fijneman, R. J. A., Vlahou, A., Zoidakis, J., & Cavic, M. (2026). Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets. Molecular Oncology. https://doi.org/10.1002/1878- 0261.70324
New project publication
IORS Dept. for Department of Genetic Counseling for Hereditary Cancer published the first systematic analysis of a clinically selected high-risk Serbian cohort related to Lynch syndrome. The manuscript provides novel data on the spectrum of LS-associated variants in this referral population, demonstrates the predominance of MLH1 variants, and supports broader implementation of genetic testing, tumor screening, and genetic counseling.
Djordjic Crnogorac M, Karadzic V, Cato T, Cavic M, Nikolic N, Spasic J, Djordjevic F, Jokic V, Kocic M, Djurasinovic M, Kukic B, Nikolic S, Ristic M, Milovic M, Krivokuca A. Genetic Landscape of Lynch Syndrome in a High-Risk Serbian Cohort: Predominance of MLH1 Variants and Implications for Risk-Based Testing. International Journal of Molecular Sciences. 2026; 27(15):6652. https://doi.org/ 10.3390/ijms27156652.


