STEPUPIORS physicians Prof. Suzana Stojanovic-Rundic and Mladen Marinkovic
were lead authors on a new project publication.
were lead authors on a new project publication.
This study evaluated the efficacy and safety of dose-escalated radiotherapy (RT) using the volumetric modulated arc therapy–simultaneous integrated boost (VMAT–SIB) technique in patients with locally advanced rectal cancer compared to 3D conformal radiotherapy (3D-CRT).
The implementation of intensified treatment with a higher dose using the VMAT–SIB technique demonstrated significant benefits in downsizing and downstaging compared to the standard treatment approach. These findings support its potential for integration into clinical practice, after carefully planned prospective, multi-center studies needed to validate the results and assess long-term outcomes.
